Document Detail

Aortic valve replacement with stentless xenografts.
MedLine Citation:
PMID:  1341637     Owner:  NLM     Status:  MEDLINE    
Between 15th June 1991 and 15th August 1992, 40 patients underwent aortic valve replacement with the newly designed Edwards stentless aortic bioprosthesis 2500. The patients' ages ranged from 24 years to 80 years (mean 60.3 years). Preoperatively, 17 patients presented with pure aortic stenosis, three with aortic regurgitation and 20 with mixed lesion. The operations were performed with normothermic extracorporeal cardiopulmonary bypass and cold cardioplegic arrest. The implanted valves ranged in diameter from 21 mm to 27 mm. Ten patients received a subcoronary implantation, with the lower row of sutures being interrupted and the upper being continuous. The so-called miniroot technique was used in the other 30, also involving lower interrupted and running upper sutures after adaptation of the coronary ostia to the preformed openings in the graft. The aortic cross-clamp time ranged from 51 minutes to 94 minutes (mean 71 minutes). There was no operative mortality but three patients died early after the operation due to cardiac tamponade, sepsis and pneumonia. There was no late mortality or morbidity in the surviving patients up to 16 months postoperatively. Echocardiography, performed at discharge and twice a year thereafter showed no signs of significant valve incompetence in any patient, and continuous wave Doppler measurements indicated that resting pressure gradients across the aortic valve were low or absent. Our preliminary experience with the stentless aortic xenograft shows improved hemodynamic function as compared to stent mounted xenografts or mechanical prostheses. Further studies are needed, however, to establish the long-term performance of this device.
W Konertz; P Hamann; E Schwammenthal; G Breithardt; H H Scheld
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of heart valve disease     Volume:  1     ISSN:  0966-8519     ISO Abbreviation:  J. Heart Valve Dis.     Publication Date:  1992 Nov 
Date Detail:
Created Date:  1994-01-25     Completed Date:  1994-01-25     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9312096     Medline TA:  J Heart Valve Dis     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  249-52     Citation Subset:  IM    
Department of Thoracic and Cardiovascular Surgery, University of Muenster, FRG.
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MeSH Terms
Aged, 80 and over
Aortic Valve / physiopathology,  surgery,  ultrasonography
Aortic Valve Insufficiency / physiopathology,  surgery
Aortic Valve Stenosis / physiopathology,  surgery
Evaluation Studies as Topic
Heart Valve Prosthesis* / methods
Middle Aged
Prosthesis Design
Suture Techniques

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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