Document Detail

Aortic valve replacement with the Cardioprotese Premium bovine pericardium bioprosthesis: four-year clinical results.
MedLine Citation:
PMID:  22588029     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: This study reports the initial clinical and echocardiographic results of the Premium bioprosthetic aortic valve up to 4 years of follow-up.
METHODS: Between October 2007 and July 2011, 121 consecutive patients were submitted for aortic valve replacement with the Premium bioprosthetic valve. The mean age was 68 ± 9 years and 64 patients were males. The patients were periodically evaluated by clinical and echocardiographic examinations. The mean follow-up was 21 months (min = 2, max = 48), yielding 217 patients/year for the analysis.
RESULTS: The hospital mortality was 8%. Late survival at 3 years was 89% (95% CI: 81.9-93.3%), and 80% of the patients were in NYHA functional class I/II. The rates of valve-related complications were low, with a linearized incidence of 0.9%/100 patients/year for thromboembolic complications, 0% for haemorrhagic events and 0.9%/100 patients/year of bacterial endocarditis. There was no case of primary structural valve dysfunction. The mean effective orifice area was 1.61 ± 0.45 cm(2); mean gradient 13 ± 5 mmHg and peak gradient 22 ± 9 mmHg. Significant patient-prosthesis mismatch was found in only 11% of the cases.
CONCLUSIONS: The Premium bioprosthetic aortic valve demonstrated very satisfactory clinical and echocardiographic results up to 4 years, similar to other commercially available, third-generation bioprosthetic valves.
Fábio Rocha Farias; Francisco Diniz Affonso da Costa; Eduardo Mendel Balbi Filho; Daniele de Fátima Fornazari; Claudinei Collatusso; Andreia Dumsch de Aragon Ferreira; Sergio Veiga Lopes; Tadeu Augusto Fernandes
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Publication Detail:
Type:  Journal Article     Date:  2012-05-15
Journal Detail:
Title:  Interactive cardiovascular and thoracic surgery     Volume:  15     ISSN:  1569-9285     ISO Abbreviation:  Interact Cardiovasc Thorac Surg     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-07-17     Completed Date:  2012-11-19     Revised Date:  2013-08-14    
Medline Journal Info:
Nlm Unique ID:  101158399     Medline TA:  Interact Cardiovasc Thorac Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  229-34     Citation Subset:  IM    
Division of Cardiovascular Surgery, Santa Casa de Misericórdia de Curitiba-PUCPR and Instituto de Neurologia e Cardiologia de Curitiba, Paraná, Brazil.
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MeSH Terms
Aged, 80 and over
Aortic Valve / surgery*,  ultrasonography
Disease-Free Survival
Heart Valve Diseases / mortality,  surgery*,  ultrasonography
Heart Valve Prosthesis Implantation / adverse effects,  instrumentation*,  mortality
Heart Valves*
Hospital Mortality
Kaplan-Meier Estimate
Middle Aged
Pericardium / transplantation*
Postoperative Complications / etiology,  mortality
Prosthesis Design
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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