Document Detail

Aortic valve noncoronary cusp thrombosis after implantation of a nonpulsatile, continuous-flow pump.
MedLine Citation:
PMID:  23109752     Owner:  NLM     Status:  MEDLINE    
Different institutions have different strategies for managing both native and prosthetic aortic valves in recipients of left ventricular assist devices (LVADs). Anticoagulation protocols and pump-flow algorithms remain nonstandardized. We describe our institutional experience with thrombotic complications and our evolving approach to this important clinical problem. We report the cases of 4 HeartMate II LVAD recipients in whom, despite an anticoagulative regimen, thrombus formed on the noncoronary cusp of the aortic valve. The management of the closed aortic valve in LVAD-supported patients remains problematic.
Zumrut T Demirozu; O H Frazier
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital     Volume:  39     ISSN:  1526-6702     ISO Abbreviation:  Tex Heart Inst J     Publication Date:  2012  
Date Detail:
Created Date:  2012-10-30     Completed Date:  2013-04-10     Revised Date:  2013-07-11    
Medline Journal Info:
Nlm Unique ID:  8214622     Medline TA:  Tex Heart Inst J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  618-20     Citation Subset:  IM    
Department of Cardiovascular Surgery, Texas Heart Institute at St. Luke's Episcopal Hospital, Houston, Texas 77030, USA.
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MeSH Terms
Anticoagulants / therapeutic use
Aortic Valve* / surgery,  ultrasonography
Fatal Outcome
Heart Failure / therapy*
Heart Transplantation
Heart Valve Diseases / etiology*,  therapy,  ultrasonography
Heart-Assist Devices / adverse effects*
Middle Aged
Prosthesis Design
Thrombosis / etiology*,  therapy,  ultrasonography
Treatment Outcome
Reg. No./Substance:

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