| Aortic stiffness is an independent predictor of progression to hypertension in nonhypertensive subjects. | |
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MedLine Citation:
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PMID: 15710784 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Aortic stiffness may predict progression to hypertension beyond classic risk factors. In a longitudinal study, we assessed the predictive value of aortic stiffness on future hypertension in nonhypertensive subjects with blood pressure (BP) <140/90. Aortic stiffness was determined by echocardiography at baseline in 2512 subjects. The follow-up time was 4 years. A stepwise increase in hypertension incidence occurred across the male and older participants: 3.8% of young female individuals, 11.5% of young male, 26.1% of old female, and 58.8% of old male subjects progressed to hypertension over 4 years. In multivariate analysis, aortic stain, distensibility, and stiffness index (beta) remained significantly associated with the progression to future hypertension after adjustment to classic risk factors in men and women and in young and old populations. This study provides the first direct evidence to our knowledge in a longitudinal study that aortic stiffness is an independent predictor of progression to hypertension in nonhypertensive individuals. |
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Authors:
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John Dernellis; Maria Panaretou |
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Publication Detail:
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Type: Journal Article Date: 2005-02-14 |
Journal Detail:
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Title: Hypertension Volume: 45 ISSN: 1524-4563 ISO Abbreviation: Hypertension Publication Date: 2005 Mar |
Date Detail:
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Created Date: 2005-02-25 Completed Date: 2005-10-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7906255 Medline TA: Hypertension Country: United States |
Other Details:
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Languages: eng Pagination: 426-31 Citation Subset: IM |
Affiliation:
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Department of Cardiology, Vostanion Hospital, Mytilini, Greece. dernellis@yahoo.gr |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Age Distribution Aged Aged, 80 and over Aorta / physiopathology*, ultrasonography Compliance Echocardiography Female Follow-Up Studies Humans Hypertension / epidemiology, etiology* Incidence Longitudinal Studies Male Middle Aged Multivariate Analysis Predictive Value of Tests Sex Distribution |
| Comments/Corrections | |
Comment In:
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Hypertension. 2005 Mar;45(3):349-51
[PMID:
15710783
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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