Document Detail


Aortic stenosis: clinical aspects of diagnosis and management, with 10 illustrative case reports from a 25-year experience.
MedLine Citation:
PMID:  21057260     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Aortic stenosis (AS) is a chronic, progressive disease predominantly affecting individuals aged over 60 years. Symptoms are the result of progressive left ventricular outflow obstruction, and herald rapid clinical decline and high mortality. Medical therapies for AS remain ineffective; operative valve replacement remains the only effective long-term treatment. We review clinical aspects of diagnosis and management of AS in adults, with attention to the natural history before and after valve replacement, assessment of suspected and established AS, and recommended management in general and in difficult clinical scenarios. We conclude with a series of 10 cases illustrating management of common, uncommon, and challenging clinical scenarios encountered at the University of Washington.
Authors:
Christopher E Kurtz; Catherine M Otto
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Medicine     Volume:  89     ISSN:  1536-5964     ISO Abbreviation:  Medicine (Baltimore)     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-08     Completed Date:  2010-12-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985248R     Medline TA:  Medicine (Baltimore)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  349-79     Citation Subset:  AIM; IM    
Affiliation:
Division of Cardiology, University of Washington, Seattle, Washington 98195, USA. cekurtz@u.washington.edu
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MeSH Terms
Descriptor/Qualifier:
Age Factors
Aortic Valve Stenosis* / diagnosis,  physiopathology,  surgery
Echocardiography
Exercise
Heart Valve Prosthesis Implantation*
Humans
Patient Education as Topic
Physical Examination
Prevalence
Risk Factors
Severity of Illness Index
Sex Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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