| Aortic-iliac thrombosis in horses. | |
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MedLine Citation:
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PMID: 4002537 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Vascular obstruction of the hindlimbs was diagnosed clinically in 15 horses, and was characterized at necropsy in eight of those horses. The condition was identified as an incidental post mortem finding in two additional horses. The principal clinical signs in affected horses were progressive exercise intolerance and hind-leg lameness. At post mortem the oldest lesions were located at the aortic quadrifurcation and in the distal portions of the femoral and internal iliac arteries, and consisted of partially or completely occlusive masses of well-organized and well-vascularized fibrous tissue, occasionally containing hemorrhagic or degenerate areas. Proximal to these organized masses, large unorganized thrombi were often present. In the region of the occlusive masses, the tunica intima was obliterated, except for the internal elastic lamina which usually remained intact. The tunica media was largely unaffected, except for ischemic necrosis of the media in greatly distended arteries or under thick plaques. The pathogenesis of the lesions is unresolved. The lesions may result from organization of strongyle-related thromboemboli or the inciting cause may be progressive enlargement and organization of spontaneously developing fibrous intimal plaques. Hypercoagulability of the blood may have contributed to thrombosis in one mare with the nephrotic syndrome. Routine examination of the aortic quadrifurcation and its major branches is recommended in order that subclinical changes may be detected and the natural history of the lesion elucidated. |
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Authors:
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M G Maxie; P W Physick-Sheard |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Veterinary pathology Volume: 22 ISSN: 0300-9858 ISO Abbreviation: Vet. Pathol. Publication Date: 1985 May |
Date Detail:
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Created Date: 1985-07-17 Completed Date: 1985-07-17 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0312020 Medline TA: Vet Pathol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 238-49 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Aorta / pathology Aortic Diseases / pathology, veterinary* Female Horse Diseases / pathology* Horses Iliac Artery* / pathology Lameness, Animal / etiology Male Strongyle Infections, Equine / pathology Thrombosis / pathology, veterinary* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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