| Aortic dissection in pregnancy: a life-threatening disease and a diagnosis of worth considering. | |
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MedLine Citation:
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PMID: 19707897 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Acute aortic dissection is a life-threatening disease. To increase the awareness of this diagnosis as a cause of feto-maternal mortality during pregnancy, we have analyzed risk factors using information from five pregnant women admitted for acute aortic dissection to the Karolinska University Hospital over an eight-year period (1999-2007). Four of the women died and only one survived. One fetus was stillborn and all newborn infants showed signs of asphyxia at birth. Of the women, who were on average five years above the mean age for delivery in Sweden, three had hypertension, two had first-degree relatives with aortic dissection which had occurred during the second half of pregnancy (gestational age at diagnosis 26-41 weeks). The most common presenting symptoms were severe back, abdominal and leg pain, and confusion. If a rapid diagnosis is not made, the risk of mortality for both mother and fetus is high. The incidence of aortic rupture during pregnancy in Sweden appears to be 14.5/1,000,000 and the case maternal fatality ratio 4.4/1,000,000. |
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Authors:
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Josefine Nasiell; Mikael Norman; Pelle G Lindqvist; Jonas Malmstedt; Roger Bottinga; Mats Blennow |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Acta obstetricia et gynecologica Scandinavica Volume: 88 ISSN: 1600-0412 ISO Abbreviation: Acta Obstet Gynecol Scand Publication Date: 2009 |
Date Detail:
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Created Date: 2009-11-20 Completed Date: 2009-12-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370343 Medline TA: Acta Obstet Gynecol Scand Country: England |
Other Details:
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Languages: eng Pagination: 1167-70 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Karolinska University Hospital, Stockholm, Sweden. Josefine.Nasiell@karolinska.se |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aneurysm, Dissecting / diagnosis*, epidemiology Aortic Aneurysm / diagnosis*, epidemiology Fatal Outcome Female Humans Maternal Mortality Pregnancy Pregnancy Complications, Cardiovascular / diagnosis*, epidemiology Sweden / epidemiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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