Document Detail


Aortic, cerebral and lower limb arterial and venous response to orthostatic stress after a 60-day bedrest.
MedLine Citation:
PMID:  21541764     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The objective of this study is to assess by echography and Doppler the Cerebral (Vmca), Aortic (Vao) and Femoral (Vfem) arterial flow velocity and calf vein (Tibial, Gastrocnemius) section (Tib, Gast) during orthostatic intolerance (OI) test after a 60-day, head down tilt bed rest (HDBR). Twenty-four women (25-40 years) underwent a 60-day HDBR at -6°: eight as control (Con), eight with exercise against lower body negative pressure (Ex-Lb) and eight with nutrition supplement (Nut). Before and after (R0) HDBR, all subjects underwent a 10-min, 80° tilt followed by progressive LBNP until presyncope. After the post-HDBR Tilt + LBNP test, two groups were identified: finishers (F, n = 11) who completed the Tilt and non-finishers (NF, n = 13). A higher percentage decrease in Vao flow, higher percentage distension of Tib vein and a lack of increase in Vmca/Vfem ratio during the post-HDBR Tilt + LBNP compared to pre-HDBR were correlated to OI, but not all of these abnormal responses were present in each of the NF subjects. Abnormal responses were more frequent in Con and Nut than in Ex-Lb subjects. (1) HDBR did not affect the cardiac, arterial and venous responses to the orthostatic test to the same extent in each subject. (2) Exercise within LBNP partially preserved the cardiovascular response to Tilt, while Nutrition supplementation had no efficacy. (3) Cerebral/femoral flow ratio and aortic flow were the parameters most closely related to OI. (4) Reduction in aortic flow was not the major hemodynamic change preceding syncope.
Authors:
P Arbeille; K Shoemaker; P Kerbeci; S Schneider; A Hargens; R Hughson
Related Documents :
2957344 - Effect of epinephrine on local cutaneous blood flow.
22568874 - Graphene transistor as a probe for streaming potential.
3947524 - Is driving gas flow rate clinically important for nebulizer therapy?
11007564 - Venoarterial co(2) difference during regional ischemic or hypoxic hypoxia.
9120854 - Respiratory and circulatory parameters of african elephants (loxodonta africana) anaest...
6533924 - Towards automation of single needle vascular access.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-5-4
Journal Detail:
Title:  European journal of applied physiology     Volume:  -     ISSN:  1439-6327     ISO Abbreviation:  -     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-5-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100954790     Medline TA:  Eur J Appl Physiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
CERCOM-UMPS Med Physiol spatiale, University-CHU Trousseau, Tours, France, arbeille@med.univ-tours.fr.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Biobehavioral markers of adverse effect in fetal alcohol spectrum disorders.
Next Document:  Anticipatory scaling of grip forces when lifting objects of everyday life.