Document Detail

Aortic Stiffness Increased in Spinal Cord Injury when Matched for Physical Activity.
MedLine Citation:
PMID:  22688833     Owner:  NLM     Status:  Publisher    
PURPOSE: To compare arterial stiffness between those with spinal cord injury (SCI) and able bodied (AB) individuals when matched for habitual level of physical activity. METHODS: A total of 17 SCI and 17 AB were matched for sex, age, weight, blood pressure and levels of self reported habitual physical activity (Godin-Shephard). Measures included central (cfPWV) and lower limb (ftPWV) pulse wave velocity as well as large and small arterial compliance. RESULTS: The cfPWV was significantly elevated (7.3 ± 2.1 vs. 5.7 ± 1.4 m/s, P < 0.05) in SCI compared to AB. No other measures of arterial stiffness were different between groups. Moderate to vigorous physical activity was significantly correlated with both large (r = 0.48, P < 0.05) and small (r = 0.65, P < 0.01) artery compliance, but not cfPWV or ftPWV. CONCLUSIONS: Both large and small artery compliance appear to be associated with habitual physical activity in physically active individuals with SCI. However, we did not show that physical activity is associated with PWV in physically active individuals with SCI. These findings suggest that factors other than physical inactivity may mediate the increase in arterial stiffness widely reported in the SCI population.
Aaron A Phillips; Anita T Cote; Shannon S D Bredin; Andrei V Krassioukov; Andrei V Krassioukov; Darren E R Warburton
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-8
Journal Detail:
Title:  Medicine and science in sports and exercise     Volume:  -     ISSN:  1530-0315     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8005433     Medline TA:  Med Sci Sports Exerc     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
1Cardiovascular Physiology and Rehabilitation Laboratory, Physical Activity Promotion and Chronic Disease Prevention Unit, University of British Columbia, Vancouver, Canada 2Experimental Medicine Program, Faculty of Medicine, University of British Columbia, Vancouver, Canada 3Cognitive and Functional Learning Laboratory, University of British Columbia, Canada 4International Collaboration of Repair Discoveries, University of British Columbia, Vancouver, British Columbia, Canada 5Division of Physical Medicine and Rehabilitation, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
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