| Aortic pressures, stiffness and left ventricular function in coronary slow flow phenomenon. | |
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MedLine Citation:
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PMID: 20798537 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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BACKGROUND: Coronary slow flow (CSF) phenomenon is characterized by delayed opacification of coronary vessels in a normal coronary angiogram. Although clinical and pathological features have been previously described, the underlying pathophysiology has not been fully elucidated. In this study, we aimed to evaluate central aortic pressure, aortic stiffness and left ventricular (LV) function in patients with coronary slow flow. METHOD AND RESULTS: The study population consisted of 154 patients who underwent coronary angiography because of typical and quasi-typical symptoms of angina. 81 patients with angiographically proven CSF and 73 cases with normal coronary flow pattern with similar risk profiles were enrolled in the study. Aortic pressures and indexes of elastic properties were evaluated using invasive methods. Aortic pulse pressure (mm Hg) and pulsality index of patients with CSF were found to be significantly higher than those of controls (60.8 ± 13.8 vs. 53.7 ± 14.5, p = 0.002; 0.84 ± 0.22 vs. 0.67 ± 0.18, p = 0.0001, respectively). LV Doppler parameters were deteriorated in patients with CSF. Aortic fractional pulse pressure and pulsality index were significantly correlated with the mean TIMI frame count and LV diastolic parameters in correlation analysis. CONCLUSION: The present findings allow us to conclude that impaired aortic elasticity in patients with CSF may also be responsible for the impaired LV diastolic parameters. |
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Authors:
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Halil Tanriverdi; Harun Evrengul; I Dogu Kilic; Ozgur Taskoylu; Güllü Dogan; Seref Alpsoy |
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Publication Detail:
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Type: Journal Article Date: 2010-08-26 |
Journal Detail:
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Title: Cardiology Volume: 116 ISSN: 1421-9751 ISO Abbreviation: Cardiology Publication Date: 2010 |
Date Detail:
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Created Date: 2010-10-13 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 1266406 Medline TA: Cardiology Country: Switzerland |
Other Details:
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Languages: eng Pagination: 261-7 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 S. Karger AG, Basel. |
Affiliation:
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Department of Cardiology, Pamukkale University School of Medicine, Denizli, Turkey. drhaliltanriverdi@yahoo.com.tr |
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Comment In:
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Cardiology. 2010;116(4):257-60
[PMID:
20798536
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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