| Aortic Atherosclerotic Plaque and Long-Term Prognosis in Patients With Atrial Fibrillation. | |
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MedLine Citation:
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PMID: 23047295 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Background: Both left atrial spontaneous echo contrast (LASEC) and aortic atherosclerotic plaque (AoP) ≥4.0mm in thickness are predictors of cardiovascular events after stroke. The aim of this study was to investigate impact of AoP ≥4.0mm or LASEC on cardiovascular events in patients with atrial fibrillation (AF). Methods and Results: One hundred and eight consecutive patients with AF were enrolled and studied. Patients were grouped according to the presence or absence of AoP ≥4.0mm in the proximal aortic arch on transesophageal echocardiography (TEE). Cardiovascular events included death, myocardial infarction, ischemic stroke, systemic embolism and congestive heart failure. During a follow-up period (median, 3.9 years), cardiovascular event-free survival rate was significantly lower in patients with AoP ≥4.0mm than in patients without AoP ≥4.0mm (log-rank, P=0.01). In contrast, patients with LASEC showed a trend toward lower cardiovascular event-free survival than those without LASEC (log-rank, P=0.10). Univariate TEE predictors of cardiovascular events were AoP ≥4.0mm, LASEC and left atrial appendage flow velocity. On multivariate Cox regression analysis, AoP ≥4.0mm was the only TEE predictor of cardiovascular events during follow-up (P=0.02, hazard ratio, 2.6; 95% confidence interval: 1.1-6.0). Conclusions: In the present unselected patients with AF, AoP predicted long-term cardiovascular events. |
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Authors:
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Hiroyuki Okura; Toru Kataoka; Minoru Yoshiyama; Junichi Yoshikawa; Kiyoshi Yoshida |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-10-06 |
Journal Detail:
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Title: Circulation journal : official journal of the Japanese Circulation Society Volume: - ISSN: 1347-4820 ISO Abbreviation: Circ. J. Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-10-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101137683 Medline TA: Circ J Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Division of Cardiology, Bell Land General Hospital. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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