Document Detail


Anxiety sensitivity and response to cholecystokinin tetrapeptide in healthy volunteers.
MedLine Citation:
PMID:  8238648     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The authors determined whether fear of anxiety symptoms mediates panicogenic responses to cholecystokinin tetrapeptide (CCK-4) in healthy subjects. Individuals with a preexisting high level of anxiety sensitivity (N = 10) experienced significantly more catastrophic cognitions and fear of somatic symptoms than did subjects with low (N = 9) or medium (N = 17) anxiety sensitivity, but they were not more susceptible to experiencing a panic attack. Thus, cognitive factors do not appear to be critical determinants of CCK-4-induced panic attacks.
Authors:
D Koszycki; B J Cox; J Bradwejn
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of psychiatry     Volume:  150     ISSN:  0002-953X     ISO Abbreviation:  Am J Psychiatry     Publication Date:  1993 Dec 
Date Detail:
Created Date:  1993-12-17     Completed Date:  1993-12-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370512     Medline TA:  Am J Psychiatry     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1881-3     Citation Subset:  AIM; IM    
Affiliation:
Department of Psychiatry, St. Mary's Hospital Center, Montreal, Que., Canada.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Anxiety / chemically induced*
Blood Pressure / drug effects
Cognition / drug effects*
Fear / drug effects
Female
Heart Rate / drug effects
Humans
Male
Panic Disorder / chemically induced*
Personality Inventory
Tetragastrin / pharmacology*
Chemical
Reg. No./Substance:
1947-37-1/Tetragastrin
Comments/Corrections
Comment In:
Am J Psychiatry. 1995 Feb;152(2):300-1   [PMID:  7840376 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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