| Anxiety, neuroticism and oxidative stress: cross-sectional study in non-smoking college students. | |
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MedLine Citation:
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PMID: 20653910 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: Oxidative stress has gained attention recently in psychiatric medicine and has been reported to be associated with various diseases. However, the psychosocial factors involved in oxidative stress are still not well understood. Thus, the aim of this study was to examine whether anxiety levels and neuroticism were associated with serum oxidative and anti-oxidative status in healthy college students. METHODS: Participants in this cross-sectional study were 54 non-smoking college students. Their serum oxidative status was determined by reactive oxygen metabolites (ROM) and the biological anti-oxidant potential. Anxiety levels and neuroticism were assessed using the State-Trait Anxiety Inventory and the NEO Five-Factor Inventory, respectively. RESULTS: Correlation analysis showed an association of increased ROM concentration with elevated anxiety levels (State, rho = 0.39, P = 0.046; Trait, rho = 0.44, P = 0.024) and the personality trait of neuroticism (rho = 0.47, P = 0.016) in female students. However, the ROM concentration in male students was not associated with the anxiety level or any personality trait. CONCLUSION: Although these findings suggest that neurotic and anxious female students tend to be exposed to oxidative stress, these linkages should be confirmed by multivariate analysis in future research. |
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Authors:
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Masateru Matsushita; Takayuki Kumano-Go; Nakamori Suganuma; Hiroyoshi Adachi; Schuhei Yamamura; Hiroko Morishima; Yoshihisa Shigedo; Akira Mikami; Masatoshi Takeda; Yoshiro Sugita |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Psychiatry and clinical neurosciences Volume: 64 ISSN: 1440-1819 ISO Abbreviation: Psychiatry Clin. Neurosci. Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-26 Completed Date: 2010-11-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9513551 Medline TA: Psychiatry Clin Neurosci Country: Australia |
Other Details:
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Languages: eng Pagination: 435-41 Citation Subset: IM |
Affiliation:
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Psychiatry, Department of Integrated Medicine, Division of Internal Medicine, Osaka University Graduate School of Medicine, Osaka, Japan. matsushit@psy.med.osaka-u.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anxiety
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metabolism*,
physiopathology Chi-Square Distribution Cross-Sectional Studies Female Humans Male Neurotic Disorders / metabolism*, physiopathology Oxidative Stress* / physiology Personality / physiology Personality Inventory Reactive Oxygen Species / blood Sex Factors Statistics, Nonparametric Students / psychology Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Reactive Oxygen Species |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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