| Antral hypergastrinemia--a report of three cases. | |
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MedLine Citation:
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PMID: 3678636 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Three patients with juxtapyloric ulcers and hypergastrinemia are presented. Fasting and food-stimulated serum gastrin concentration (SGC) were measured in 1970, 1972 and 1973 before the primary ulcer operation (selective gastric vagotomy and Jaboulay gastroduodenostomy; SGV + GD). Fasting SGC were 105, 149 and 158 pg/ml and the postprandial concentrations were 400, greater than 800 and greater than 800 pg/ml, respectively. The pentagastrin-stimulated acid secretion was within the normal range. After SGV + GD, only a slight decrease in acid secretion was observed. The hypergastrinemia persisted unchanged or decreased slightly in 1 patient. A recurrent ulcer developed and a precise antrectomy was carried out. Postoperatively, the fasting SGC was markedly reduced and the postprandial gastrin response abolished. The resected specimens were subjected to immunocytochemical gastrin cell quantitation. The number of gastrin cells was elevated in all 3 patients and the gastrin cell topography was distorted, with cells being present both in the lower and upper thirds of the antropyloric glands. |
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Authors:
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J Poulsen; P Delikaris; L I Larsson; E Amdrup |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Digestion Volume: 37 ISSN: 0012-2823 ISO Abbreviation: Digestion Publication Date: 1987 |
Date Detail:
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Created Date: 1988-01-11 Completed Date: 1988-01-11 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0150472 Medline TA: Digestion Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 211-6 Citation Subset: IM |
Affiliation:
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Department of Surgical Gastroenterology, Kommunehospitalet, Arhus University, Denmark. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Gastric Acid / secretion* Gastrins / blood*, secretion Humans Hyperplasia Male Middle Aged Pyloric Antrum / metabolism, pathology, surgery Radioimmunoassay Recurrence Stomach Ulcer / blood*, pathology, surgery |
| Chemical | |
Reg. No./Substance:
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0/Gastrins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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