Document Detail


Antiviral aptamers.
MedLine Citation:
PMID:  17851732     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Aptamers are rare nucleic acid ligands, which can be concocted in the laboratory from the randomized pool of molecules by affinity and amplification processes. Aptamers have several properties as they can be applied complementarily to antibodies and have several advantages over antibodies. In the past, several aptamers have been selected with a view to develop antiviral agents for therapeutic applications. This review summarizes potent antiviral aptamers and their strategies to prevent the viral replication.
Authors:
S C B Gopinath
Publication Detail:
Type:  Journal Article; Review     Date:  2007-09-14
Journal Detail:
Title:  Archives of virology     Volume:  152     ISSN:  0304-8608     ISO Abbreviation:  Arch. Virol.     Publication Date:  2007  
Date Detail:
Created Date:  2007-12-06     Completed Date:  2008-04-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7506870     Medline TA:  Arch Virol     Country:  Austria    
Other Details:
Languages:  eng     Pagination:  2137-57     Citation Subset:  IM    
Affiliation:
Functional Nucleic Acids Group, Institute for Biological Resources and Functions and Center for Applied Near Field Optics Research, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan. gopi-subashchandrabose@aist.go.jp
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MeSH Terms
Descriptor/Qualifier:
Antiviral Agents / therapeutic use*
Aptamers, Nucleotide / therapeutic use*
Humans
Virus Diseases / drug therapy*
Chemical
Reg. No./Substance:
0/Antiviral Agents; 0/Aptamers, Nucleotide

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