| Antitumor activity of N-diazoacetyl derivatives of glycine and phenylalanine against P388 leukemia and B16 melanoma in mice. | |
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MedLine Citation:
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PMID: 6796268 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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N-Diazoacetyl derivatives of glycine and phenylalanine show antitumor activity in mice bearing P388 leukemia or B16 melanoma. The presented data indicate that antitumor activity is shown by diazomethylamide derivatives of glycine and phenylalanine, in addition to that already established for the amino acid derivatives having an O-diazoacetyl group (azaserine) or a diazoketone structure (DON and azotomycin) and for 1,2-bis-diazoacetyl ethane. |
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Authors:
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G Sava; T Giraldi; L Baldini |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Cancer treatment reports Volume: 66 ISSN: 0361-5960 ISO Abbreviation: Cancer Treat Rep Publication Date: 1982 Jan |
Date Detail:
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Created Date: 1982-02-25 Completed Date: 1982-02-25 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7607107 Medline TA: Cancer Treat Rep Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 179-81 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Antineoplastic Agents* Azo Compounds / therapeutic use* Glycine / analogs & derivatives, therapeutic use* Leukemia, Experimental / drug therapy* Melanoma / drug therapy* Mice Neoplasms, Experimental / drug therapy |
| Chemical | |
Reg. No./Substance:
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0/Antineoplastic Agents; 0/Azo Compounds; 56-40-6/Glycine; 820-75-7/N-diazoacetylglycine hydrazide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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