| Antithromboxane drug in the treatment of preeclampsia. | |
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MedLine Citation:
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PMID: 1756996 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In this study, we present our initial trials in the treatment of 6 cases of severe preeclampsia with thromboxane synthetase inhibitor (OKY-046). Following the treatment with OKY-046, maternal systolic blood pressure decreased significantly and umbilical artery waveforms were normalized. These data suggest that thromboxane synthetase inhibition might have a beneficial effect on preeclampsia. |
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Authors:
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N Furuhashi; M Tsujiei; H Kimura; K Okamura; A Yajima |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Gynecologic and obstetric investigation Volume: 32 ISSN: 0378-7346 ISO Abbreviation: Gynecol. Obstet. Invest. Publication Date: 1991 |
Date Detail:
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Created Date: 1992-02-06 Completed Date: 1992-02-06 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7900587 Medline TA: Gynecol Obstet Invest Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 164-6 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Tohoku University School of Medicine, Sendai, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Drug Evaluation Female Humans Methacrylates / therapeutic use* Pre-Eclampsia / drug therapy* Pregnancy Thromboxane-A Synthase / antagonists & inhibitors* |
| Chemical | |
Reg. No./Substance:
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0/Methacrylates; 82571-53-7/ozagrel; EC 5.3.99.5/Thromboxane-A Synthase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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