Document Detail

Antithromboxane drug in the treatment of preeclampsia.
MedLine Citation:
PMID:  1756996     Owner:  NLM     Status:  MEDLINE    
In this study, we present our initial trials in the treatment of 6 cases of severe preeclampsia with thromboxane synthetase inhibitor (OKY-046). Following the treatment with OKY-046, maternal systolic blood pressure decreased significantly and umbilical artery waveforms were normalized. These data suggest that thromboxane synthetase inhibition might have a beneficial effect on preeclampsia.
N Furuhashi; M Tsujiei; H Kimura; K Okamura; A Yajima
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Gynecologic and obstetric investigation     Volume:  32     ISSN:  0378-7346     ISO Abbreviation:  Gynecol. Obstet. Invest.     Publication Date:  1991  
Date Detail:
Created Date:  1992-02-06     Completed Date:  1992-02-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7900587     Medline TA:  Gynecol Obstet Invest     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  164-6     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Tohoku University School of Medicine, Sendai, Japan.
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MeSH Terms
Drug Evaluation
Methacrylates / therapeutic use*
Pre-Eclampsia / drug therapy*
Thromboxane-A Synthase / antagonists & inhibitors*
Reg. No./Substance:
0/Methacrylates; 82571-53-7/ozagrel; EC Synthase

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