| Antithrombotic lipids from Semen Persicae. | |
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MedLine Citation:
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PMID: 21899477 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Chemical investigation of Semen Persicae has led to the isolation of decane (1), triolein (2), nonacosanoic acid (3), oleic acid ethyl ester (4), palmitic acid (5), oleic acid (6) and 15,16-dihydroxy-9Z,12Z-octadecadienoic acid 2,3-dihydroxypropyl ester (7). Amongst these, compound 7 is a new lipid. Their structures were elucidated by chemical and extensive spectral analysis. Their anticoagulative activities were also evaluated in vitro, which showed that petroleum ether extract and compounds 5-6 could significantly prolong thrombin time while methanol extract could obviously inhibit platelet aggregation. |
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Authors:
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Nian-Yun Yang; Li Liu; Wei-Wei Tao; Jin-Ao Duan; Xun-Hong Liu; Su-Ping Huang |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-9-8 |
Journal Detail:
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Title: Natural product research Volume: - ISSN: 1478-6427 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-9-8 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101167924 Medline TA: Nat Prod Res Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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a Jiangsu Key Laboratory for TCM Formulae Research , Nanjing University of Traditional Chinese Medicine , Nanjing 210046 , China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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