Document Detail


Antithrombins and coronary artery disease.
MedLine Citation:
PMID:  6731355     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The role of antithrombin-III with respect to atherogenesis and myocardial infarction remains unclear; however, it has been reported that antithrombin-III levels are decreased in many individuals with coronary artery disease and in those at high risk for coronary artery occlusion. However, the several reports available do not agree and remain inconclusive. Antithrombin-III levels were determined in 86 individuals undergoing coronary artery angiography. Results of these determinations reveal that the majority of patients with angiographically documented coronary artery disease have normal antithrombin-III levels. Additionally, there was found to be no correlation between antithrombin-III levels and severity or site of coronary artery involvement. The results of this study would suggest that plasma antithrombin-III determinations are of no particular significance in determining the presence, absence, or severity of coronary artery disease.
Authors:
R L Bick; D Faulstick
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of clinical pathology     Volume:  81     ISSN:  0002-9173     ISO Abbreviation:  Am. J. Clin. Pathol.     Publication Date:  1984 Jun 
Date Detail:
Created Date:  1984-07-09     Completed Date:  1984-07-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370470     Medline TA:  Am J Clin Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  773-5     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Antithrombin III / analysis*
Coronary Disease / blood*,  classification,  diagnosis
Humans
Chemical
Reg. No./Substance:
9000-94-6/Antithrombin III

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