| Antithrombin III levels in term and preterm infants measured by rate nephelometry. | |
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MedLine Citation:
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PMID: 6477763 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The plasma antithrombin III level was measured in term and premature newborns within the first 24 h of life; in addition to the authors', own immunological method utilizing rate nephelometry the assays of Laurell and Kabi Coatest were used. Antithrombin III concentration showed a linear correlation with the degree of maturity, in accordance with previous data. The lowest values were found in premature babies affected by idiopathic respiratory distress syndrome who later developed pulmonary haemorrhage. At all gestational ages the antithrombin III functional index was lower than 1.0, indicating antithrombin III consumption. Since both concentration and activity of antithrombin III are low in prematures, they are at an increased risk for coagulopathies, hence substitution therapy is indicated. Measurement of antithrombin III by rate nephelometry can also be used for following changes in inhibitor concentration. |
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Authors:
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L Karmazsin; G Balla; M Misz; P Beck; P Nagy; K Rák |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta paediatrica Hungarica Volume: 25 ISSN: 0001-6527 ISO Abbreviation: Acta Paediatr Hung Publication Date: 1984 |
Date Detail:
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Created Date: 1984-11-02 Completed Date: 1984-11-02 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8307729 Medline TA: Acta Paediatr Hung Country: HUNGARY |
Other Details:
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Languages: eng Pagination: 119-26 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antithrombin III
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analysis* Gestational Age Humans Infant, Newborn* Infant, Premature* Nephelometry and Turbidimetry |
| Chemical | |
Reg. No./Substance:
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9000-94-6/Antithrombin III |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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