Document Detail

Antitetanus immunity in a sample of adult population from the Siena area (Italy).
MedLine Citation:
PMID:  3228499     Owner:  NLM     Status:  MEDLINE    
1045 subjects (427 males and 618 females) from the Siena area, aged 20-85, were screened for tetanus antitoxin by the means of a passive haemogglutination assay. 32% of subjects was found protected against tetanus (antitoxin titre greater than or equal to 0.1 I.U./ml), 34.7% resulted partially protected (titre greater than or equal to 0.01 - less than 0.1 I.U./ml), and 33.3% was found unprotected (titre less than 0.01 I.U./ml). The protection rate was higher among males (44.9%) than among females (23%) and showed a definite age-related decrease. Within each age group, the protection rate was higher among males. The lowest protection rate (3.2%) was observed among females aged 70 or more. Analysis of the protection rate according to the individuals' occupation showed the highest value (44.9%) among workmen and the lowest (12.1%) among housewives. The anamnestic criterion was found exceedingly unreliable to assess the individual's immune status. Results, which are consistent with present tetanus italian epidemiology, are discussed for their implications relating to a possible improvement of current antitenus immunization policy.
C Cellesi; G M Rossolini; G Dirienzo; R Petrini; C Marsili; P Addari; A Zanchi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bollettino dell'Istituto sieroterapico milanese     Volume:  67     ISSN:  0021-2547     ISO Abbreviation:  Boll Ist Sieroter Milan     Publication Date:  1988  
Date Detail:
Created Date:  1989-04-13     Completed Date:  1989-04-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  17720040R     Medline TA:  Boll Ist Sieroter Milan     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  149-55     Citation Subset:  IM    
Istituto di Clinica delle Malattie Infettive dell'Università di Siena, Italy.
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MeSH Terms
Aged, 80 and over
Immunization / standards,  utilization*
Immunization Schedule
Middle Aged
Random Allocation
Tetanus / immunology*
Tetanus Toxoid / analysis,  immunology*
Reg. No./Substance:
0/Tetanus Toxoid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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