Document Detail

Antiretroviral treatment 2010: progress and controversies.
MedLine Citation:
PMID:  21045599     Owner:  NLM     Status:  MEDLINE    
Effective antiretroviral therapy (ART) changes the clinical course of HIV infection. There are 25 antiretroviral drugs approved for the treatment of HIV infection, and current antiretroviral drug regimens are highly effective, convenient, and relatively nontoxic. ART regimens should be chosen in consideration of a patient's particular clinical situation. Successful treatment is associated with durable suppression of HIV viremia over years, and consequently, ART reduces the risk of clinical progression. In fact, current models estimate that an HIV-infected individual appropriately treated with antiretroviral drugs has a life expectancy that approaches that of the general HIV-uninfected population, although some patient groups such as injection drug users do less well. Despite these advances, continued questions about ART persist: What is the optimal time to start ART? What is the best regimen to start? When is the optimal time to change ART? What is the best regimen to change to? In addition, newer antiretroviral agents are in development, both in existing classes and in new classes such as the CD4 receptor attachment inhibitors and the maturation inhibitors. Further research will help optimize current antiretroviral treatments and strategies.
Roy M Gulick
Related Documents :
17217329 - Cardiovascular risks of antiretroviral therapies.
18462589 - Does antiretroviral therapy prevent hiv transmission to sexual partners?
21045599 - Antiretroviral treatment 2010: progress and controversies.
9499329 - Response of lymphoepithelial parotid cysts to antiretroviral treatment in hiv-infected ...
21323099 - Eruptive kaposi sarcoma: an unusual presentation in an hiv-negative patient.
23080229 - The role of ccaat enhancer-binding protein homologous protein in human immunodeficiency...
11575869 - Orofacial effects of antiretroviral therapies.
10493469 - Reliability and validity of french, german, italian, dutch, and uk english translations...
9779929 - Induction of matrix metalloproteinase-2 in human immunodeficiency virus-1 glycoprotein ...
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Journal of acquired immune deficiency syndromes (1999)     Volume:  55 Suppl 1     ISSN:  1944-7884     ISO Abbreviation:  J. Acquir. Immune Defic. Syndr.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-03     Completed Date:  2010-11-22     Revised Date:  2014-09-08    
Medline Journal Info:
Nlm Unique ID:  100892005     Medline TA:  J Acquir Immune Defic Syndr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S43-8     Citation Subset:  IM; X    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Anti-HIV Agents / administration & dosage,  therapeutic use*
Drug Administration Schedule
HIV Infections / drug therapy*
Grant Support
Reg. No./Substance:
0/Anti-HIV Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Infectious disease comorbidities adversely affecting substance users with HIV: hepatitis C and tuber...
Next Document:  Opportunities to diagnose, treat, and prevent HIV in the criminal justice system.