| Antiretroviral Preexposure Prophylaxis for HIV Prevention. | |
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MedLine Citation:
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PMID: 23281986 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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To the Editor: Thigpen et al. (Aug. 2 issue)(1) report that persons who are seronegative for the human immunodeficiency virus (HIV) and who are receiving tenofovir disoproxil fumarate and emtricitabine (TDF-FTC) for preexposure prophylaxis had decreased bone mineral density at 24 months, as compared with those receiving placebo. In HIV-infected cohorts, TDF causes an initial loss of bone density over a period of 6 to 12 months, but there is stable bone density subsequently.(2),(3) These findings are consistent with other studies that have shown short-term loss of bone density in patients initiating antiretroviral treatment but stable bone density in . . . |
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Authors:
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Mark J Bolland; Andrew Grey |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The New England journal of medicine Volume: 368 ISSN: 1533-4406 ISO Abbreviation: N. Engl. J. Med. Publication Date: 2013 Jan |
Date Detail:
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Created Date: 2013-01-03 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0255562 Medline TA: N Engl J Med Country: United States |
Other Details:
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Languages: eng Pagination: 82-4 Citation Subset: AIM; IM |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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