| Antipsychotic treatment in schizophrenia: the role of computerized neuropsychological assessment. | |
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MedLine Citation:
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PMID: 18982837 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The present study analyzes the role of neurocognitive assessment instruments in the detection of the contribution of antipsychotic treatment to cognitive functioning. Recently, a panel of experts suggested six main domains (working memory; attention/vigilance; verbal/visual learning and memory; reasoning and problem solving; speed of processing) implicated in schizophrenia-related cognitive deficits, which serve as a theoretical base for creation of real-time computerized neurocognitive batteries. The high sensitivity of computerized neuropsychological testing is based on their ability to adopt the reaction time (RT) paradigm for the assessment of brain function in a real-time regime. This testing is highly relevant for the monitoring of the cognitive effects of antipsychotics. Computerized assessment assists in the identification of state- and trait-related cognitive impairments. The optimal real-time computerized neurocognitive battery should composite balance between broad and narrow coverage of cognitive domains relevant to the beneficial effects of antipsychotics and will enable better planning of treatment and rehabilitation programs. |
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Authors:
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Semion Kertzman; Ilya Reznik; Haim Grinspan; Abraham Weizman; Moshe Kotler |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: The Israel journal of psychiatry and related sciences Volume: 45 ISSN: 0333-7308 ISO Abbreviation: Isr J Psychiatry Relat Sci Publication Date: 2008 |
Date Detail:
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Created Date: 2008-11-05 Completed Date: 2008-12-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8108287 Medline TA: Isr J Psychiatry Relat Sci Country: Israel |
Other Details:
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Languages: eng Pagination: 114-20 Citation Subset: IM |
Affiliation:
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Forensic Psychiatry Division, Beer-Yakov Mental Health Center, POB 1, Beer-Yakov 70300, Israel. kertzman@animascan.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antipsychotic Agents
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therapeutic use* Cognition Disorders / diagnosis*, etiology* Diagnosis, Computer-Assisted* Humans Neuropsychological Tests* Reaction Time Schizophrenia / complications*, drug therapy* |
| Chemical | |
Reg. No./Substance:
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0/Antipsychotic Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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