| Antipsychotic drugs and relapse prevention. | |
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MedLine Citation:
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PMID: 10190229 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Strategies for preventing relapse during the maintenance or stable phase of schizophrenia are discussed for both conventional and newer antipsychotics. For conventional agents, strategies focus on finding dosages that minimize antipsychotic drug side effects and provide adequate protection against psychotic relapse. Although few studies are available to compare older and newer antipsychotics for preventing relapse, there are reasons for proposing that newer drugs will be shown to be superior. Because of their milder side effects, clinicians can choose drug dosages that provide maximum protection against relapse. Further, since patients on the newer drugs are likely to experience fewer discomforting side effects, they may be more likely to take their medications as directed. Other potential advantages of the newer drugs over the older drugs include the likelihood that they are more effective against negative and cognitive symptoms of schizophrenia. |
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Authors:
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S R Marder |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Schizophrenia research Volume: 35 Suppl ISSN: 0920-9964 ISO Abbreviation: Schizophr. Res. Publication Date: 1999 Mar |
Date Detail:
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Created Date: 1999-07-21 Completed Date: 1999-07-21 Revised Date: 2010-09-02 |
Medline Journal Info:
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Nlm Unique ID: 8804207 Medline TA: Schizophr Res Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: S87-92 Citation Subset: IM |
Affiliation:
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Psychiatry Service, West Los Angeles Veterans Affairs Medical Center, CA 90073, USA. marder@ucla.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Antipsychotic Agents
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therapeutic use* Benzodiazepines Clozapine / therapeutic use Humans Pirenzepine / analogs & derivatives, therapeutic use Recurrence / prevention & control Risperidone / therapeutic use Schizophrenia / drug therapy* |
| Chemical | |
Reg. No./Substance:
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0/Antipsychotic Agents; 106266-06-2/Risperidone; 12794-10-4/Benzodiazepines; 132539-06-1/olanzapine; 28797-61-7/Pirenzepine; 5786-21-0/Clozapine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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