Document Detail


Antipsychotic-associated weight gain and clinical outcome parameters.
MedLine Citation:
PMID:  11346191     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Weight gain has been observed with many of the antipsychotics, including the atypical antipsychotics. The assessment of whether, and to what degree, a drug causes changes in body weight is not straightforward, since clinical studies performed during a drug development program are not designed to measure changes in body weight. Even when weight change data are obtained from adverse event data or from part of the vital signs measured during a study, assessment is not standardized. Nevertheless, evidence points to the fact that weight gain with the atypical antipsychotics is becoming an increasing problem. This review examines whether antipsychotic-associated weight gain, when it occurs, is associated with clinical outcome parameters.
Authors:
O Blin; J Micallef
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  The Journal of clinical psychiatry     Volume:  62 Suppl 7     ISSN:  0160-6689     ISO Abbreviation:  J Clin Psychiatry     Publication Date:  2001  
Date Detail:
Created Date:  2001-05-10     Completed Date:  2001-05-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7801243     Medline TA:  J Clin Psychiatry     Country:  United States    
Other Details:
Languages:  eng     Pagination:  11-21     Citation Subset:  IM    
Affiliation:
Centre de Pharmacologie Clinique et d'Evaluatións Therapeutiques, H pital de la Timone, Marseille, France. oblin@mail.ap.hm.fr
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MeSH Terms
Descriptor/Qualifier:
Ambulatory Care
Antipsychotic Agents / adverse effects*,  therapeutic use*
Clinical Trials as Topic / statistics & numerical data
Female
Hospitalization
Humans
Male
Obesity / chemically induced
Outcome Assessment (Health Care)
Psychotic Disorders / drug therapy*
Schizophrenia / drug therapy
Treatment Outcome
Weight Gain / drug effects*
Chemical
Reg. No./Substance:
0/Antipsychotic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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