Document Detail

Antipruritic effect of natural superoxide dismutase--sensory evaluation.
MedLine Citation:
PMID:  19818223     Owner:  NLM     Status:  MEDLINE    
The primary objective of the study was to evaluate the antipruritic effect of natural superoxide dismutase in the cosmetic product Sodermix cream. In this randomized intra-individual study including 15 volunteers, 14 female and one male, mean age 41 +/- 4 (range 18-66) years, the cosmetic product Sodermix cream was evaluated according to the Dermscan Group protocol by recording thermal sensitivity levels using Cutaneous Thermal Sensitivity analyzer before and 30 and 90 minutes after the product application. The study was conducted from April to June 2008. Study results showed a decrease in the lengths of pruritus 30 minutes of the product application onto the treated zone and a significant decrease in pruritus intensity 90 minutes of the product application onto the treated zone. The study allows for evaluation of physical sensation and quantification of heat with cutaneous thermal sensitivity measurements as a psycho-physical method to evaluate variables of thermal sensations in relation to variables by thermal stimuli. The study demonstrated a significant antipruritic effect of Sodermix cream.
Christian Diehl; Elsa Vaurillon; Jasna Lipozencić
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Acta dermatovenerologica Croatica : ADC     Volume:  17     ISSN:  1330-027X     ISO Abbreviation:  Acta Dermatovenerol Croat     Publication Date:  2009  
Date Detail:
Created Date:  2009-10-12     Completed Date:  2010-08-26     Revised Date:  2011-09-13    
Medline Journal Info:
Nlm Unique ID:  9433781     Medline TA:  Acta Dermatovenerol Croat     Country:  Croatia    
Other Details:
Languages:  eng     Pagination:  217-25     Citation Subset:  IM    
Hospital de Clinicas, Universidad Nacional de Cordoba, Santa Rosa, Cordoba, Argentina.
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MeSH Terms
Middle Aged
Pruritus / drug therapy*
Skin / drug effects
Superoxide Dismutase / administration & dosage,  therapeutic use*
Thermosensing / drug effects
Time Factors
Treatment Outcome
Reg. No./Substance:
0/Ointments; EC Dismutase

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