Document Detail

Antiplatelet versus anticoagulant therapies in advanced age: an unfinished task.
MedLine Citation:
PMID:  16343666     Owner:  NLM     Status:  MEDLINE    
We have read with great interest a retrospective cohort study recently published by Blich and Gross. In our opinion, this article renews the controversy of the best antithrombotic therapy in patients with AF. The use of anticoagulant treatment to prevent the occurrence of stroke in patients with AF is supported by several randomized controlled clinical trials. Aspirin is also effective in preventing stroke in AF, but both direct and indirect comparisons with oral anticoagulation suggest less effectiveness. However, very probably these patients are quite different than those seen in the clinical practice. The role of antiplatelet therapy is not completely established, and the selection between aspirin or warfarin in advanced age remains an unfinished task.
Antonio García-Honrubia; Vanessa Roldán; Vicente Climent; Francisco Sogorb; Francisco Marín
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Publication Detail:
Type:  Comment; Comparative Study; Letter     Date:  2005-12-15
Journal Detail:
Title:  International journal of cardiology     Volume:  110     ISSN:  0167-5273     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-05-29     Completed Date:  2006-11-02     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  271-2     Citation Subset:  IM    
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MeSH Terms
Anticoagulants / therapeutic use*
Aspirin / therapeutic use*
Atrial Fibrillation / drug therapy
Cohort Studies
Platelet Aggregation Inhibitors / therapeutic use*
Retrospective Studies
Stroke / prevention & control
Warfarin / therapeutic use*
Reg. No./Substance:
0/Anticoagulants; 0/Platelet Aggregation Inhibitors; 50-78-2/Aspirin; 81-81-2/Warfarin
Comment On:
Int J Cardiol. 2004 Jul;96(1):89-95   [PMID:  15203266 ]

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