Document Detail

Antiplatelet therapy in coronary heart disease. Emerging strategies for the treatment and prevention of acute myocardial infarction.
MedLine Citation:
PMID:  8418769     Owner:  NLM     Status:  MEDLINE    
Platelets, long recognized for their role in physiological (protective) hemostasis, have been shown conclusively to play an intricate role in both coronary arterial atherogenesis and acute thrombosis. Accordingly, antiplatelet agents have emerged as a prominent feature in treatment strategies designed to prevent and directly confront the progression and thrombotic complications of coronary heart disease in humans. Antiplatelet therapy, used alone or in combination with thrombin antagonists and thrombolytics must be explored with continued enthusiasm to assure growth of this treatment modality.
R C Becker
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Archives of pathology & laboratory medicine     Volume:  117     ISSN:  0003-9985     ISO Abbreviation:  Arch. Pathol. Lab. Med.     Publication Date:  1993 Jan 
Date Detail:
Created Date:  1993-02-04     Completed Date:  1993-02-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7607091     Medline TA:  Arch Pathol Lab Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  89-96     Citation Subset:  AIM; IM    
Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester 01655.
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MeSH Terms
Blood Platelets / drug effects,  physiology*
Coronary Disease / blood,  drug therapy*,  prevention & control*
Fibrinolytic Agents / therapeutic use*
Myocardial Infarction / blood,  drug therapy*,  prevention & control*
Platelet Activation*
Platelet Aggregation
Platelet Aggregation Inhibitors / therapeutic use*
Thrombolytic Therapy*
Reg. No./Substance:
0/Fibrinolytic Agents; 0/Platelet Aggregation Inhibitors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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