Document Detail

Antiphospholipid syndrome: review.
MedLine Citation:
PMID:  16004169     Owner:  NLM     Status:  MEDLINE    
Antiphospholipid syndrome spans many medical disciplines. Classic criteria include the presence of anticardiolipin antibody or lupus anticoagulant with typical complications of thrombosis or pregnancy loss. Other common associated manifestations include livedo reticularis, thrombocytopenia, valvular heart disease, and nephropathy with renal insufficiency, hypertension, and proteinuria. Treatment of serious complications with anticoagulation is standard; generally warfarin for thrombosis and aspirin/heparin for pregnancy prophylaxis. Detailed recommendations regarding precise intensity and duration of anticoagulation are still a subject of debate.
Lisa R Sammaritano
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Southern medical journal     Volume:  98     ISSN:  0038-4348     ISO Abbreviation:  South. Med. J.     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-07-11     Completed Date:  2005-07-21     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0404522     Medline TA:  South Med J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  617-25; quiz 626-7, 645     Citation Subset:  AIM; IM    
Weill Medical College of Cornell University, Hospital of Special Surgery, New York, NY 10021, USA.
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MeSH Terms
Antibodies, Antiphospholipid / analysis
Anticoagulants / therapeutic use
Antiphospholipid Syndrome / complications,  diagnosis*,  drug therapy
Lupus Coagulation Inhibitor / analysis
Pregnancy Complications
Pregnancy Outcome
Reg. No./Substance:
0/Antibodies, Antiphospholipid; 0/Anticoagulants; 0/Lupus Coagulation Inhibitor

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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