Document Detail

Antiphospholipid syndrome and pregnancy loss.
MedLine Citation:
PMID:  9829058     Owner:  NLM     Status:  MEDLINE    
Antiphospholipid antibodies (aPL) are associated with recurrent miscarriage. Pregnancies that survive the first trimester risk developing pre-eclampsia, intrauterine growth retardation and fetal distress during labour. Pregnancy loss is initially caused by defective embryonic implantation and later by thrombosis of the placental vasculature. In women with aPL, thromboprophylaxis during pregnancy improves the live birth rate.
R Rai; L Regan
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Hospital medicine (London, England : 1998)     Volume:  59     ISSN:  1462-3935     ISO Abbreviation:  Hosp Med     Publication Date:  1998 Aug 
Date Detail:
Created Date:  1998-12-03     Completed Date:  1998-12-03     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9803882     Medline TA:  Hosp Med     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  637-9     Citation Subset:  IM    
Department of Obstetrics and Gynaecology, Hillingdon Hospital, Uxbridge.
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MeSH Terms
Abortion, Habitual / etiology*,  prevention & control
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
Anticoagulants / therapeutic use
Antiphospholipid Syndrome / complications*,  diagnosis
Aspirin / therapeutic use
Diabetes Mellitus, Type 1 / complications
Heparin / therapeutic use
Pregnancy in Diabetics / complications
Reg. No./Substance:
0/Anti-Inflammatory Agents, Non-Steroidal; 0/Anticoagulants; 50-78-2/Aspirin; 9005-49-6/Heparin

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