| Antiphospholipid syndrome: long-time research on pathogenic mechanisms has finally lead to new therapeutic strategies. | |
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MedLine Citation:
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PMID: 21058919 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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The antiphospholipid syndrome is characterized by the presence of arterial or venous thrombosis or recurrent miscarriages in a patient with positive laboratory tests for antiphospholipid antibodies (anticardiolipin antibodies and/or lupus anticoagulant and/or anti-beta2-glycoprotein I). Despite the strong association between antiphospholipid antibodies and thrombosis and obstetric morbidity, their pathogenic role in the development of these clinical features has not been fully elucidated. However, the knowledge of new pathogenic mechanisms might identify novel therapeutic targets and therefore may improve the management of these patients. |
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Authors:
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Ricard Cervera; Gerard Espinosa |
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Publication Detail:
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Type: Editorial |
Journal Detail:
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Title: Expert opinion on therapeutic targets Volume: 14 ISSN: 1744-7631 ISO Abbreviation: Expert Opin. Ther. Targets Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-09 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101127833 Medline TA: Expert Opin Ther Targets Country: England |
Other Details:
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Languages: eng Pagination: 1279-82 Citation Subset: IM |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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