| Antiphospholipid antibody syndrome: coexistence of left ventricular apical thrombus and deep vein thrombosis causing pulmonary thromboembolism in a patient with systemic lupus erythematosus. | |
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MedLine Citation:
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PMID: 20113328 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report a 36-year-old woman with a 1-year history of systemic lupus erythematosus who was admitted with acute onset of dyspnea and chest pain. She presented with a classic medical history of antiphospholipid antibody syndrome, including spontaneous abortion, deep venous thrombosis, and clinical manifestations of lupus activation. The differential diagnosis was made after a detailed history and examinations with transthoracic/transesophageal echocardiography, deep venous ultrasonography, chest computed tomography, and coronary angiography. This case demonstrates a left ventricular apical thrombus in angiographically normal coronary arteries and also deep vein thrombosis causing acute pulmonary thromboembolism. Antiaggregant and anticoagulant therapies were initiated as a result of the presence of a left ventricular apical thrombus and deep venous thrombosis, which is predisposed to recurrent pulmonary or systemic embolization. Control echocardiography demonstrated resolution of apical thrombus and normalized left ventricular systolic function after aspirin, warfarin, and immunosuppressive therapy for 2 months. |
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Authors:
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Sadik Acikel; Ramazan Akdemir; Mehmet Dogan; Harun Kilic; Asuman Bicer Yesilay |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-01-22 |
Journal Detail:
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Title: Echocardiography (Mount Kisco, N.Y.) Volume: 27 ISSN: 1540-8175 ISO Abbreviation: Echocardiography Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-04-12 Completed Date: 2010-07-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8511187 Medline TA: Echocardiography Country: United States |
Other Details:
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Languages: eng Pagination: 198-201 Citation Subset: IM |
Affiliation:
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Department of Cardiology, Ministry of Health Dişkapi Yildirim Beyazit Research and Educational Hospital, Ankara, Turkey. sadik.acikel@tkd.org.tr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antiphospholipid Syndrome / complications, ultrasonography* Female Humans Lupus Erythematosus, Systemic / etiology, ultrasonography* Pulmonary Embolism / etiology, ultrasonography* Venous Thrombosis / etiology, ultrasonography* Ventricular Dysfunction, Left / etiology, ultrasonography* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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