Document Detail


Antiperinuclear factor and antibodies to the stratum corneum of rat esophagus in juvenile idiopathic arthritis.
MedLine Citation:
PMID:  10190929     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We analyzed the frequency and clinical correlates of antiperinuclear factor (APF) and antibodies to the stratum corneum of rat esophagus in 86 children with juvenile idiopathic arthritis (JIA), 32 children with juvenile systemic lupus erythematosus, and 52 healthy children. Forty-two patients with JIA (49%) were positive for APF. No association was observed between APF and current age, sex, JIA subtype, age at disease onset, or disease duration. APF was found in one patient with juvenile systemic lupus erythematosus and in no healthy child. Antibodies to the stratum corneum of rat esophagus were detected in 3 patients with polyarticular JIA. APF may be a valuable tool in the differential diagnosis of JIA.
Authors:
C R Serra; S H Rodrigues; F R Sztajnbok; N P Silva; L E Andrade
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of pediatrics     Volume:  134     ISSN:  0022-3476     ISO Abbreviation:  J. Pediatr.     Publication Date:  1999 Apr 
Date Detail:
Created Date:  1999-04-30     Completed Date:  1999-04-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  507-9     Citation Subset:  AIM; IM    
Affiliation:
Division of Rheumatology, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.
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MeSH Terms
Descriptor/Qualifier:
Animals
Antibodies / blood*
Antibodies, Antinuclear / blood*
Arthritis, Juvenile Rheumatoid / blood*
Child, Preschool
Female
Fluorescent Antibody Technique, Indirect
Humans
Keratins / immunology*
Lupus Erythematosus, Systemic / blood
Male
Rats
Reference Values
Rheumatoid Factor / blood
Chemical
Reg. No./Substance:
0/Antibodies; 0/Antibodies, Antinuclear; 0/antiperinuclear factor; 68238-35-7/Keratins; 9009-79-4/Rheumatoid Factor

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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