| Antioxidant synergism of green tea polyphenols with alpha-tocopherol and L-ascorbic acid in SDS micelles. | |
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MedLine Citation:
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PMID: 18554517 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The synergistic antioxidant effect of polyphenols extracted from green tea, i.e. (-)-epicatechin (EC), (-)-epigallocatechin (EGC), (-)-epicatechin gallate (ECG), (-)-epigallocatechin gallate (EGCG) and gallic acid (GA), with alpha-tocopherol (vitamin E) and L-ascorbic acid (vitamin C) against the peroxidation of linoleic acid has been studied in sodium dodecyl sulfate (SDS) micelles. The peroxidation was initiated thermally by a water-soluble azo initiator 2,2'-azobis(2-amidinopropane) hydrochloride (AAPH), and the reaction kinetics were studied by monitoring the formation of linoleic acid hydroperoxides and consumption of the antioxidants. It was found that the mixture of the green tea polyphenol, vitamin E and vitamin C could act synergistically to protect lipid peroxidation. Kinetic and mechanistic studies on the antioxidation process revealed that this antioxidant synergism was due to the regeneration of vitamin E by the green tea polyphenol and the regeneration of the latter by vitamin C. |
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Authors:
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Fang Dai; Wei-Feng Chen; Bo Zhou |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2008-05-23 |
Journal Detail:
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Title: Biochimie Volume: 90 ISSN: 0300-9084 ISO Abbreviation: Biochimie Publication Date: 2008 Oct |
Date Detail:
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Created Date: 2008-09-12 Completed Date: 2008-11-26 Revised Date: 2010-04-23 |
Medline Journal Info:
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Nlm Unique ID: 1264604 Medline TA: Biochimie Country: France |
Other Details:
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Languages: eng Pagination: 1499-505 Citation Subset: IM |
Affiliation:
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State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, Gansu, China. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antioxidants
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metabolism,
pharmacology* Ascorbic Acid / metabolism, pharmacology* Catechin / analogs & derivatives, metabolism Complex Mixtures / metabolism, pharmacology Flavonoids / metabolism, pharmacology* Free Radicals / pharmacology Half-Life Kinetics Linoleic Acid / metabolism Lipid Peroxidation / drug effects Micelles* Phenols / metabolism, pharmacology* Sodium Dodecyl Sulfate* Tea / chemistry* alpha-Tocopherol / metabolism, pharmacology* |
| Chemical | |
Reg. No./Substance:
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0/Antioxidants; 0/Complex Mixtures; 0/Flavonoids; 0/Free Radicals; 0/Micelles; 0/Phenols; 0/Tea; 0/polyphenols; 151-21-3/Sodium Dodecyl Sulfate; 154-23-4/Catechin; 2197-37-7/Linoleic Acid; 50-81-7/Ascorbic Acid; 59-02-9/alpha-Tocopherol; 863-03-6/epicatechin gallate |
| Comments/Corrections | |
Erratum In:
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Biochimie. 2009 Nov-Dec;91(11-12):1535 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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