| Antioxidant properties of raisins (Vitis vinifera L.). | |
| | |
MedLine Citation:
|
PMID: 20041785 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Currants and sultanas (Vitis vinifera L., Family Vitaceae) are dried vine products produced in Greece and used widely in the Mediterranean diet. We investigated the polar methanol extracts from the raisins for the antiradical activity, polyphenol content, cytotoxicity in peripheral blood mononuclear cells, total glutathione (GSH) levels, oxidized glutathione (GSSG) levels, and inhibition of low-density lipoprotein (LDL) oxidation. Extracts exhibited 1,1-diphenyl-2-picrylhydrazyl scavenging activity and inhibited tert-butylhydroperoxide (tBHP)-induced cytotoxicity, GSH decrease, and LDL oxidation. Fluorescence microscopy revealed the characteristic apoptotic patterns with tBHP and inhibition with the extracts. Elevated levels of total GSH and unaltered levels of GSSG with extract treatment demonstrated the induction of gamma-glutamylcysteine synthetase. The antioxidant activity was correlated to the polyphenolic content. Greek currants and sultanas are suggested as antioxidant components of the Mediterranean basin. |
| | |
Authors:
|
Andriana C Kaliora; Aggeliki M Kountouri; Vaios T Karathanos |
Related Documents
:
|
11767105 - Phenolic compounds of chromolaena odorata protect cultured skin cells from oxidative da... 18222035 - Correlation between oxidation potentials and inhibitory effects on epstein-barr virus a... 19021795 - Antioxidant activities of polyphenolic compounds isolated from antidesma thwaitesianum ... 20024105 - Pyridine and pyrimidine analogs of acetaminophen as inhibitors of lipid peroxidation an... 186485 - Functional and physicochemical studies of hemoglobin st. louis beta 28 (b10) leu replac... 20950895 - Novel conformationally restricted triazole derivatives with potent antifungal activity. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Journal of medicinal food Volume: 12 ISSN: 1557-7600 ISO Abbreviation: J Med Food Publication Date: 2009 Dec |
Date Detail:
|
Created Date: 2009-12-31 Completed Date: 2010-03-05 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9812512 Medline TA: J Med Food Country: United States |
Other Details:
|
Languages: eng Pagination: 1302-9 Citation Subset: IM |
Affiliation:
|
Department of Science of Dietetics-Nutrition, Harokopio University, Athens, Greece. akaliora@hua.gr |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Antioxidants
/
analysis,
pharmacology* Cell Survival / drug effects Cells, Cultured Flavonoids / analysis, pharmacology Free Radical Scavengers / metabolism Glutathione Disulfide / metabolism Humans Leukocytes, Mononuclear / cytology, drug effects, metabolism Phenols / analysis, pharmacology Plant Extracts / analysis, pharmacology* Vitis / chemistry* |
| Chemical | |
Reg. No./Substance:
|
0/Antioxidants; 0/Flavonoids; 0/Free Radical Scavengers; 0/Phenols; 0/Plant Extracts; 0/polyphenols; 27025-41-8/Glutathione Disulfide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Chemical composition and anti-stress effects of yeast hydrolysate.
Next Document: Flavonoid-rich fraction from Sageretia theezans leaves scavenges reactive oxygen radical species and...