Document Detail


Antioxidant levels in cord blood of low birth weight newborns.
MedLine Citation:
PMID:  18695279     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We evaluated the antioxidant status of 82 healthy term low birth weight (LBW) newborns and equal number of gestation and sex matched controls weighing <2500 g by measuring vitamin A and E, superoxide dismutase, catalase and glutathione peroxidase in cord serum. Levels of vitamin A and E, superoxide dismutase and catalase were significantly lower and glutathione peroxidase significantly higher in LBW babies compared to controls, with the lowest levels found in babies showing more severe growth restriction (<2000 g). We conclude that LBW newborns are deficient in several important antioxidants which may predispose them to higher oxidative stress.
Authors:
Ashok Kumar; Rajiv Ranjan; Sriparna Basu; H D Khanna; V Bhargava
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian pediatrics     Volume:  45     ISSN:  0019-6061     ISO Abbreviation:  Indian Pediatr     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2008-08-12     Completed Date:  2008-10-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985062R     Medline TA:  Indian Pediatr     Country:  India    
Other Details:
Languages:  eng     Pagination:  583-5     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University,Varanasi, India. ashokkumar_bhu@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Antioxidants / analysis*
Catalase / analysis
Fetal Blood / chemistry*
Glutathione Peroxidase / analysis
Humans
Infant, Low Birth Weight
Infant, Newborn
Superoxide Dismutase / analysis
Vitamin A / analysis
Vitamin E / analysis
Chemical
Reg. No./Substance:
0/Antioxidants; 11103-57-4/Vitamin A; 1406-18-4/Vitamin E; EC 1.11.1.6/Catalase; EC 1.11.1.9/Glutathione Peroxidase; EC 1.15.1.1/Superoxide Dismutase

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