Document Detail

Antioxidant endogenous defense in a human model of physical stress.
MedLine Citation:
PMID:  19021027     Owner:  NLM     Status:  MEDLINE    
The present work has used controlled conditions to study how physical activity and stress affect oxidant and anti-oxidant systems in a human model. Stress test consisting of one hour exercise at a cycloergometer with intensity over the 75% of the maximal cardiac frequency was followed by non-significant changes of malonyldialdehyde, assayed as a marker of lipid peroxidation, and by an increase of erythrocyte catalase and plasma and erythrocyte glutathione peroxidase after the test. These findings suggest that antioxidant response is broadly versatile and adaptable, and that physical activity may prevent extended cellular damage with consequent flogosis. Hence, controlled physical exercise may contribute to protect target organs, including cardiovascular systems, against oxidative stress.
Fiorenzo Mignini; Daniele Tomassoni; Enea Traini; Valentino Streccioni
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical and experimental hypertension (New York, N.Y. : 1993)     Volume:  30     ISSN:  1525-6006     ISO Abbreviation:  Clin. Exp. Hypertens.     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-11-21     Completed Date:  2009-02-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9305929     Medline TA:  Clin Exp Hypertens     Country:  United States    
Other Details:
Languages:  eng     Pagination:  776-84     Citation Subset:  IM    
Sezione di Anatomia Umana, Dipartimento di Medicina Sperimentale e Sanità Pubblica, Università di Camerino, Camerino, Italy.
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MeSH Terms
Antioxidants / metabolism*
Cardiovascular Physiological Phenomena
Catalase / blood
Exercise / physiology*
Exercise Test*
Glutathione Peroxidase / blood
Hydrocortisone / blood
Lipid Peroxidation / physiology
Malondialdehyde / blood
Models, Biological*
Oxidative Stress / physiology
Stress, Physiological / physiology*
Superoxide Dismutase / blood
Time Factors
Young Adult
Reg. No./Substance:
0/Antioxidants; 50-23-7/Hydrocortisone; 542-78-9/Malondialdehyde; EC; EC Peroxidase; EC Dismutase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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