| Antioxidant activity of yellow dock (Rumex crispus L., Polygonaceae) fruit extract. | |
| | |
MedLine Citation:
|
PMID: 20623623 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
The methanol extract of ripe Rumex crispus L. fruits was evaluated for its antioxidant potential by assays for ferric-reducing antioxidant power (FRAP), DPPH-free radical scavenging activity (DPPH) and the influence on lipid peroxidation in liposomes (LP). Considerable activity was observed in all test systems (FRAP: 9.9 mmol Fe(2+) /g; DPPH IC(50) : 3.7 μg/mL; LP IC(50) : 4.9 μg/mL), comparable to that of BHT (FRAP: 8.0 μg/mL; DPPH IC(50) : 19.4 μg/mL; LP IC(50) : 3.5 μg/mL), but lower than the activity of ascorbic acid, rutin and quercetin, used as positive control substances. The in vivo effects were evaluated in several hepatic antioxidant systems (activities of LPx, GSH-Px, Px, CAT and XOD, as well as GSH content), after treatment with the studied yellow dock extract in different doses, or in combination with carbon tetrachloride (CCl(4) ). Pretreatment with the R. crispus extract inhibited CCl(4) -induced oxidative stress by decreasing LPx and increasing GSH content in a dose dependent manner, bringing the levels of antioxidant enzymes to near control values. |
| | |
Authors:
|
Zoran Maksimović; Nada Kovacević; Branislava Lakusić; Tatjana Cebović |
Related Documents
:
|
18494493 - Antioxidant potential of hydroxycinnamic acid glycoside esters. 16481163 - In vitro antioxidant activity of acetylated and benzoylated derivatives of polysacchari... 9776763 - Incorporation of terminal phosphorothioates into oligonucleotides. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Phytotherapy research : PTR Volume: 25 ISSN: 1099-1573 ISO Abbreviation: Phytother Res Publication Date: 2011 Jan |
Date Detail:
|
Created Date: 2010-12-24 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8904486 Medline TA: Phytother Res Country: England |
Other Details:
|
Languages: eng Pagination: 101-5 Citation Subset: IM |
Copyright Information:
|
Copyright © 2010 John Wiley & Sons, Ltd. |
Affiliation:
|
Institute of Pharmacognosy, School of Pharmacy, University of Belgrade, Belgrade, Serbia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Aminoglycoside-mediated partial suppression of MECP2 nonsense mutations responsible for Rett syndrom...
Next Document: Functional morphology of the gills of the shortfin mako, Isurus oxyrinchus, a lamnid shark.