Document Detail


Antioxidant activity and angiotensin I-converting enzyme inhibition by enzymatic hydrolysates from bee bread.
MedLine Citation:
PMID:  15787258     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Enzymatic hydrolysates were prepared from bee bread using three proteases. The antioxidant properties of these hydrolysates were measured using four different methods. These had remarkable antioxidant activity similar or superior to that of 1 mM alpha-tocopherol. They also had high scavenging activities against active oxygen species as the superoxide anion radical and hydroxyl radicals. Moreover, they showed angiotensin I-converting enzyme inhibitory activities and the activities were similar to those from various fermented foods such as fish sauce, sake, vinegar, cheese, miso, and natto. The present studies reveal that enzymatic hydrolysates from bee bread are of benefit not only for the materials of health food diets, but also for in patients undergoing various diseases such as cancer, cardiovascular diseases, diabetes, and hypertension.
Authors:
Takeshi Nagai; Toshio Nagashima; Nobutaka Suzuki; Reiji Inoue
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Zeitschrift für Naturforschung. C, Journal of biosciences     Volume:  60     ISSN:  0939-5075     ISO Abbreviation:  Z. Naturforsch., C, J. Biosci.     Publication Date:    2005 Jan-Feb
Date Detail:
Created Date:  2005-03-24     Completed Date:  2005-06-17     Revised Date:  2009-11-04    
Medline Journal Info:
Nlm Unique ID:  8912155     Medline TA:  Z Naturforsch C     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  133-8     Citation Subset:  IM    
Affiliation:
Department of Food Science and Technology, Tokyo University of Agriculture, Hokkaido 0992493, Japan. t1nagai@seibutu.bioindustry.nodai.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Angiotensin-Converting Enzyme Inhibitors / chemistry,  isolation & purification*,  pharmacology
Animals
Antioxidants / chemistry,  isolation & purification*,  pharmacology
Bees / metabolism*
Digestion
Free Radical Scavengers
Hydrolysis
Papain / drug effects,  metabolism
Pepsin A / drug effects,  metabolism
Peptidyl-Dipeptidase A / metabolism*
Pollen
Superoxides / metabolism
Trypsin / drug effects,  metabolism
Chemical
Reg. No./Substance:
0/Angiotensin-Converting Enzyme Inhibitors; 0/Antioxidants; 0/Free Radical Scavengers; 11062-77-4/Superoxides; EC 3.4.15.1/Peptidyl-Dipeptidase A; EC 3.4.21.4/Trypsin; EC 3.4.22.2/Papain; EC 3.4.23.1/Pepsin A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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