Document Detail

Antinuclear antibodies in patients receiving non-practolol beta-blockers.
MedLine Citation:
PMID:  23197     Owner:  NLM     Status:  MEDLINE    
Antinuclear antibodies (ANA) were found in 54 (7.0%) out of 767 treated hypertensive patients compared with 59 (2.4%) out of 2470 healthy controls. Inclusion of a non-practolol beta-blocker in the treatment regimen did not significantly affect the incidence of ANA. ANA was found in significantly more patients being treated with methyldopa (13.0%) than patients receiving other hypotensive agents (3.8%). Non-practolol beta-blockers in combination with methyldopa did not increase the incidence of ANA further.
J D Wilson; J Y Bullock; D C Sutherland; C Main; K P O'Brien
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British medical journal     Volume:  1     ISSN:  0007-1447     ISO Abbreviation:  Br Med J     Publication Date:  1978 Jan 
Date Detail:
Created Date:  1978-03-21     Completed Date:  1978-03-21     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372673     Medline TA:  Br Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  14-6     Citation Subset:  AIM; IM    
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MeSH Terms
Adrenergic beta-Antagonists / adverse effects,  therapeutic use*
Antibodies, Antinuclear / analysis*
Hypertension / drug therapy,  immunology*
Methyldopa / adverse effects,  therapeutic use*
Middle Aged
Reg. No./Substance:
0/Adrenergic beta-Antagonists; 0/Antibodies, Antinuclear; 555-30-6/Methyldopa

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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