| Antineuronal antibodies in patients with neuroblastoma: relationships with clinical features. | |
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MedLine Citation:
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PMID: 9526591 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We evaluated the frequency of serum antineuronal antibodies in a cohort of 39 neuroblastoma patients and related their presence to clinical features. Twelve patients displayed antineuronal antibodies at immunocytochemistry. Only one of these 12 patients suffered from a clinically overt paraneoplastic syndrome. No significant differences emerged between autoantibody-positive and autoantibody-negative patients in terms of progression-free and overall survival, although when only patients evolving to disease progression were considered, the time interval between diagnosis and progression was slightly longer in autoantibody-positive patients. |
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Authors:
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A Salmaggi; R Luksch; M G Forno; A Pozzi; A Silvani; A Boiardi; M Gasparini; R Nemni |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Tumori Volume: 83 ISSN: 0300-8916 ISO Abbreviation: Tumori Publication Date: 1997 Nov-Dec |
Date Detail:
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Created Date: 1998-04-07 Completed Date: 1998-04-07 Revised Date: 2008-12-12 |
Medline Journal Info:
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Nlm Unique ID: 0111356 Medline TA: Tumori Country: ITALY |
Other Details:
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Languages: eng Pagination: 953-7 Citation Subset: IM |
Affiliation:
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Istituto Nazionale Neurologico C. Besta, Milan, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Autoantibodies / blood* Blotting, Western Child Child, Preschool Cohort Studies Disease Progression Female Humans Immunohistochemistry Infant Male Neuroblastoma / immunology*, mortality, pathology Neurons / immunology* Paraneoplastic Syndromes Survival Analysis |
| Chemical | |
Reg. No./Substance:
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0/Autoantibodies |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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