Document Detail


Antimutagenic, antioxidant and free radical scavenging activity of ethyl acetate extracts from white, yellow and red onions.
MedLine Citation:
PMID:  15019191     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The beneficial effects of red, yellow and white onion extracts have been assessed by antioxidant activity and antimutagenic activity. And the effects compared to BHT and ascorbic acid. Total phenolic compounds and flavonoids in onion extracts were determined. Yellow onion extract had more organic acid and free sugar than those detected in the white and red onion extract. The scavenging activity of DPPH radical and H(2)O(2) were increased depending on the concentration. The antioxidant activities using beta-carotene-linoleate system and reducing power were increased but the effect was small to that of BHT and ascorbic acid. After digested, extracts showed antimutagenic activities, and it seems that they inhibit the mutagenicity for digesting. This study demonstrated that the antimutagenicities and antioxidant properties of ethyl acetate extract against mutagens were related to their phenols and flavonoids, which are heat stable and losses digestive juices are relatively low.
Authors:
Mi-Yae Shon; Sang-Do Choi; Goon-Gjung Kahng; Sang-Hae Nam; Nak-Ju Sung
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association     Volume:  42     ISSN:  0278-6915     ISO Abbreviation:  Food Chem. Toxicol.     Publication Date:  2004 Apr 
Date Detail:
Created Date:  2004-03-15     Completed Date:  2004-04-13     Revised Date:  2006-03-13    
Medline Journal Info:
Nlm Unique ID:  8207483     Medline TA:  Food Chem Toxicol     Country:  England    
Other Details:
Languages:  eng     Pagination:  659-66     Citation Subset:  IM    
Affiliation:
Department of Food and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University, 900 Gaza-dong chinju city, South Korea.
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MeSH Terms
Descriptor/Qualifier:
Acetates
Antimutagenic Agents* / analysis,  pharmacology
Antioxidants / analysis*
Dose-Response Relationship, Drug
Free Radical Scavengers / analysis*
Gastric Juice / drug effects,  metabolism
Intestinal Secretions / drug effects,  metabolism
Onions / chemistry*
Plant Extracts / chemistry*,  metabolism,  pharmacology
Salmonella typhimurium / drug effects,  genetics
Chemical
Reg. No./Substance:
0/Acetates; 0/Antimutagenic Agents; 0/Antioxidants; 0/Free Radical Scavengers; 0/Plant Extracts; 141-78-6/ethyl acetate

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