Document Detail


Antimutagenic activity of lipidovit.
MedLine Citation:
PMID:  15232636     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Antimutagenic properties of Lipidovit produced from the biomass of Blakeslea trispora fungi was studied by its effect on induction of chromosome aberrations by chemical mutagens dioxidine and cyclophosphamide in mouse bone marrow cells. Antimutagenic activity of Lipidovit depended on the scheme of treatment. It was maximum during pretreatment of animals (5 day) or administration in combination with mutagens (5 days). The preparation was ineffective after single administration in combination with mutagens. Lipidovit exhibited no comutagenic properties.
Authors:
P B Avchieva; V A Tyurenkov; I A Butorova; S V Deev; M I Avchiev; A V Kulakova; A D Durnev
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bulletin of experimental biology and medicine     Volume:  137     ISSN:  0007-4888     ISO Abbreviation:  Bull. Exp. Biol. Med.     Publication Date:  2004 Mar 
Date Detail:
Created Date:  2004-07-02     Completed Date:  2004-11-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372557     Medline TA:  Bull Exp Biol Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  266-9     Citation Subset:  IM    
Affiliation:
Federal State Unitary Company GosNIIsintezbelok, Moscow.
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MeSH Terms
Descriptor/Qualifier:
Animals
Antimutagenic Agents / administration & dosage,  pharmacology*
Bone Marrow Cells / drug effects
Chromosome Aberrations
Cyclophosphamide / administration & dosage,  toxicity
Male
Mice
Mice, Inbred C57BL
Mucorales / chemistry
Mutagens / administration & dosage,  toxicity
Quinoxalines / administration & dosage,  toxicity
Chemical
Reg. No./Substance:
0/Antimutagenic Agents; 0/Mutagens; 0/Quinoxalines; 17311-31-8/dioxidine; 50-18-0/Cyclophosphamide

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