Document Detail

Antimutagenic activity of caffeic acid and related compounds.
MedLine Citation:
PMID:  9063983     Owner:  NLM     Status:  MEDLINE    
Effects of caffeic acid and chlorogenic acid on mutagenicity were studied using the Salmonella typhimurium system. These compounds had inhibitory effects on the mutagenicity of Trp-P-1 and Glu-P-2. Caffeic acid completely eliminated the mutagenicity induced by activated Glu-P-2. Some compounds analogous to caffeic acid, such as cinnamic acid, coumaric acid, and ferulic acid, also significantly decreased the mutagenicity of Glu-P-2.
J Yamada; Y Tomita
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Bioscience, biotechnology, and biochemistry     Volume:  60     ISSN:  0916-8451     ISO Abbreviation:  Biosci. Biotechnol. Biochem.     Publication Date:  1996 Feb 
Date Detail:
Created Date:  1997-03-14     Completed Date:  1997-03-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9205717     Medline TA:  Biosci Biotechnol Biochem     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  328-9     Citation Subset:  B    
Laboratory of Food Science, Faculty of Education, Yamaguchi University, Japan.
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MeSH Terms
Antimutagenic Agents / pharmacology*
Caffeic Acids / pharmacology*
Chlorogenic Acid / pharmacology*
Mutagenicity Tests
Mutagens / toxicity
Reg. No./Substance:
0/Antimutagenic Agents; 0/Caffeic Acids; 0/Mutagens; 327-97-9/Chlorogenic Acid; 331-39-5/caffeic acid

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