Document Detail

Antimuscle and anti-CNS circulating antibodies in chronic fatigue syndrome.
MedLine Citation:
PMID:  9191795     Owner:  NLM     Status:  MEDLINE    
Chronic fatigue syndrome (CFS) patients suffer from disabling physical and mental fatigue. Circulating autoimmune antibodies may produce symptoms of muscular fatigue by reacting with acetylcholine receptors or calcium binding channels. They can also produce mental status changes by reacting with central nervous system (CNS) antigens. We thoroughly investigated the presence of circulating antimuscle and anti-CNS antibodies in 10 CFS patients and 10 controls. We were unable to detect any pathogenic antibodies.
A V Plioplys
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neurology     Volume:  48     ISSN:  0028-3878     ISO Abbreviation:  Neurology     Publication Date:  1997 Jun 
Date Detail:
Created Date:  1997-07-10     Completed Date:  1997-07-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1717-9     Citation Subset:  AIM; IM    
Chronic Fatigue Syndrome Center, Mercy Hospital, Chicago, IL, USA.
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MeSH Terms
Autoantibodies / blood*
Central Nervous System / immunology*
Fatigue Syndrome, Chronic / immunology*
Middle Aged
Muscle, Skeletal / immunology*
Reg. No./Substance:

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