| Antimicrobial susceptibility patterns of community-acquired uropathogens in Tehran, Iran. | |
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MedLine Citation:
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PMID: 20440056 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Antibiotic resistance of urinary tract pathogens has increased worldwide. Knowledge of the antibiotic resistance patterns of uropathogens in specific geographical locations is an important factor for choosing an appropriate empirical antimicrobial treatment. The aim of this study was to provide information regarding local resistance patterns of urinary pathogens to the commonly used antibiotics in Tehran, Iran. METHODOLOGY: Urine samples collected and submitted to two pathobiology laboratories in Tehran were identified by conventional methods over a period of three years (December 2006 to May 2009). Antimicrobial resistance testing was performed by the standard disk diffusion technique in accordance with the recommendations of the Clinical and Laboratory Standards Institute. RESULTS: Of the total 13,333 mid-stream urine samples collected from suspected cases of urinary tract infection, 840 (6.3%) were positive for pathogenic bacteria. Escherichia coli (E. coli) was the most common isolate (68.8%) followed by Proteus spp. (12.4%), and Klebsiella spp. (9.6%). E. coli isolates were mostly susceptible to nitrofurantoin (71.3%), followed by ciprofloxacin (68.1%); however, only 38.2% of E. coli isolates were susceptible to trimethoprim-sulfamethoxazole. CONCLUSION: Nitrofurantoin may be considered as a first-line empiric antibacterial agent for urinary tract infections in outpatients in Tehran, Iran. |
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Authors:
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Nasim Kashef; Gholamreza Esmaeeli Djavid; Sahba Shahbazi |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-05-01 |
Journal Detail:
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Title: Journal of infection in developing countries Volume: 4 ISSN: 1972-2680 ISO Abbreviation: J Infect Dev Ctries Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-05-04 Completed Date: 2010-07-22 Revised Date: 2010-09-14 |
Medline Journal Info:
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Nlm Unique ID: 101305410 Medline TA: J Infect Dev Ctries Country: Italy |
Other Details:
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Languages: eng Pagination: 202-6 Citation Subset: IM |
Affiliation:
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Department of Microbiology, School of Biology, College of Sciences, University of Tehran, Iran. kashefn@khayam.ut.ac.ir |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Anti-Bacterial Agents / pharmacology* Bacteria / drug effects*, isolation & purification Child Child, Preschool Community-Acquired Infections / microbiology* Female Humans Infant Iran Male Microbial Sensitivity Tests Middle Aged Urinary Tract Infections / microbiology* Urine / microbiology Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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