Document Detail


Antimicrobial proteins of maternal and cord sera and human milk in relation to maternal nutritional status.
MedLine Citation:
PMID:  2305704     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Antimicrobial proteins in maternal and cord sera and sequential samples of human milk were studied in a group of 60 Chinese women to determine the degrees of passive immunity transferred from women of different nutritional status to their infants. Maternal malnutrition was characterized by low values for wt/ht2 and serum total protein and albumin. Maternal immunoglobulin (IgG) concentrations were not significantly different between well- and malnourished groups prepartum but were significantly different postpartum. Mean concentrations of cord IgG and lysozyme from well- and malnourished groups were not statistically different. During the first 7 d of lactation and most stages thereafter, mean concentrations of IgA; complements C3 and C4, and lysozyme in milk from the malnourished group were only half of those of the well-nourished group. Antimicrobial proteins transferred via milk to newborns may be influenced by the mother's nutritional status.
Authors:
S J Chang
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  51     ISSN:  0002-9165     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  1990 Feb 
Date Detail:
Created Date:  1990-03-21     Completed Date:  1990-03-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  183-7     Citation Subset:  AIM; IM    
Affiliation:
Department of Biology, National Cheng Kung University, Tainan, Taiwan, Republic of China.
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MeSH Terms
Descriptor/Qualifier:
Blood Proteins / immunology*
Colostrum / analysis
Complement C3 / analysis
Complement C4 / analysis
Female
Fetal Blood / immunology*
Humans
Immunization, Passive
Immunoglobulin A / analysis
Immunoglobulin G / analysis
Milk Proteins / immunology*
Milk, Human / analysis,  immunology*
Muramidase / analysis
Nutritional Status*
Pregnancy
Chemical
Reg. No./Substance:
0/Blood Proteins; 0/Complement C3; 0/Complement C4; 0/Immunoglobulin A; 0/Immunoglobulin G; 0/Milk Proteins; EC 3.2.1.17/Muramidase

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