Document Detail

Antimicrobial prophylaxis in otorhinolaryngology/head and neck surgery.
MedLine Citation:
PMID:  17550515     Owner:  NLM     Status:  MEDLINE    
Prophylactic antimicrobial therapy is defined as the administration of an antimicrobial agent prior to contamination of previously sterile tissues or fluids, in an attempt to reduce the microbial burden of intraoperative contamination. Prophylactic antimicrobial therapy should cover the anticipated floral contamination, with therapeutic levels from incision to closure. There is level I evidence to support the use of prophylaxis in clean-contaminated head and neck procedures and tonsillectomy, while level II evidence fails to support the use of prophylaxis in clean head and neck procedures. The aim of this study was to evaluate the use, timing and appropriateness of antimicrobial prophylaxis perioperatively, in otorhinolaryngological/head and neck procedures. A total of 34/51 (66%) patients were administered antimicrobial agents prophylactically. Six of 19 patients (42%) who ought to have received prophylaxis did not, while six of 13 (46%) of those who did not require it received it. Administration was unsuitably timed in 14 of 34 (41%) operations. This study demonstrates unnecessary administration of antimicrobial agents perioperatively, subclinical intraoperative antimicrobial levels for prophylaxis and inconsistent documentation regarding prophylaxis in otorhinolaryngological/head and neck procedures in a general ENT unit.
B G Fennessy; M Harney; M J O'Sullivan; C Timon
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery     Volume:  32     ISSN:  1749-4478     ISO Abbreviation:  -     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-06-06     Completed Date:  2007-07-31     Revised Date:  2008-07-21    
Medline Journal Info:
Nlm Unique ID:  101247023     Medline TA:  Clin Otolaryngol     Country:  England    
Other Details:
Languages:  eng     Pagination:  204-7     Citation Subset:  IM    
Department of Otorhinolaryngology, The Royal Victoria Eye and Ear Hospital, Dublin, Ireland.
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MeSH Terms
Aged, 80 and over
Antibiotic Prophylaxis*
Child, Preschool
Middle Aged
Otorhinolaryngologic Diseases / surgery*
Prospective Studies
Surgical Wound Infection / prevention & control*
Unnecessary Procedures
Comment In:
Clin Otolaryngol. 2008 Apr;33(2):153; author reply 153   [PMID:  18429876 ]
Clin Otolaryngol. 2007 Oct;32(5):405; author reply 406   [PMID:  17883575 ]
Clin Otolaryngol. 2008 Apr;33(2):152; author reply 152   [PMID:  18429874 ]

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