| Antimicrobial properties, antioxidant activity and cytotoxicity of ethanol-soluble acidic components from Ganoderma atrum. | |
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MedLine Citation:
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PMID: 22198608 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The aim of this study was to investigate the possibility of ethanol-soluble acidic components (ESAC) from Ganoderma atrum as a novel source against bacteria and oxidation in food industry. The qualitative analysis of ESAC was based on liquid chromatography-mass spectrometry (LC/MS) and eight ganoderic acids were identified in ESAC. Its total phenolic content of ESAC was 75.80±5.67mg/g. ESAC exhibited antimicrobial activity against all of the tested bacteria (Staphylococcus aureus subsp. Aureus, Escherichia coli, Bacillus subtilis and Proteusbacillus vulgaris), and exerted antioxidant activities by 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, total reducing power and β-carotene bleaching assays. Moreover, ESAC (at concentrations of 0-100μg/mL) did not show any cytotoxic effects in RAW264.7 murine macrophage cells. Our findings suggested that ESAC has the potential as a novel natural source for food industry, ganoderic acids and phenolic compounds may be related to its antimicrobial properties as well as antioxidant activities. |
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Authors:
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Wen-Juan Li; Shao-Ping Nie; Xiao-Zhen Liu; Hui Zhang; Ying Yang; Qiang Yu; Ming-Yong Xie |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-12-16 |
Journal Detail:
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Title: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association Volume: - ISSN: 1873-6351 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-26 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8207483 Medline TA: Food Chem Toxicol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011. Published by Elsevier Ltd. |
Affiliation:
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State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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